10β,17β-dihydroxyestra-1,4-dien-3-one
Code | Size | Price |
---|
TAR-T10036-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T10036-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
10β,17β-dihydroxyestra-1,4-dien-3-one is a brain-targeting bioprecursor prodrug of the main human estrogen, 17β-estradiol. It alleviates hot flushes in rat models of thermoregulatory dysfunction of the brain.
CAS:
549-02-0
Formula:
C18H24O3
Molecular Weight:
288.387
Purity:
0.98
SMILES:
[H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C=C[C@]12O
References
1. Merchenthaler I, et al. Treatment with an orally bioavailable prodrug of 17?-estradiol alleviates hot flushes without hormonal effects in the periphery. Sci Rep. 2016 Aug 1;6:30721.