Naltrindole hydrochloride
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Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Naltrindole hydrochloride is a highly potent and selective antagonist of non-peptide δ opioid receptor(Ki of 0.02 nM).
CAS:
111469-81-9
Formula:
C26H27ClN2O3
Molecular Weight:
450.96
Pathway:
GPCR/G Protein; Endocrinology/Hormones; Neuroscience
Purity:
0.98
SMILES:
Cl.[H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)Cc1c2[nH]c2ccccc12)ccc3O
Target:
Opioid Receptor
References
1. Fern?ndez B, et al. Postnatal naltrindole treatments induce behavioural modifications in preweanling rats. Neurosci Lett. 2000 Mar 31;283(1):73-6.
2. Mundra JJ, et al. Naltrindole inhibits human multiple myeloma cell proliferation in vitro and in a murine xenograft model in vivo. J Pharmacol Exp Ther. 2012 Aug;342(2):273-87.
3. Chen YL, et al. Inhibition of akt/protein kinase B signaling by naltrindole in small cell lung cancer cells.