Acitretin
| Code | Size | Price |
|---|
| TAR-T1330-1mL | 1 mL * 10 mM (in DMSO) | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T1330-100mg | 100mg | £160.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Acitretin is a second-generation, systemic retinoid that has been used in the treatment of psoriasis.
CAS:
55079-83-9
Formula:
C21H26O3
Molecular Weight:
326.436
Pathway:
Apoptosis; Autophagy; Metabolism
Purity:
0.9995
SMILES:
COc1cc(C)c(C=CC(C)=CC=CC(C)=CC(O)=O)c(C)c1C
Target:
Apoptosis; Retinoid Receptor; Autophagy
References
1. Tippmann F, et al. FASEB J, 2009, 23(6), 1643-1654.
2. Silva FS, et al. Toxicology, 2013, 306, 93-100.
3. Lin XY, et al. J Cell Mol Med, 2009, 13(9A), 2888-2898.
4. Cotler S, et al. Xenobiotica, 1992, 22(11), 1229-1237.
5. Eisenhardt EU, et al. Drug Metab Dispos, 1994, 22(1), 26-30.
6. Qiu Y, Sun Y, Xu D, et al. Screening of FDA-approved drugs identifies sutent as a modulator of UCP1 expression in brown adipose tissue[J]. EBioMedicine. 2018, 37: 344-355.