BMS493
| Code | Size | Price |
|---|
| TAR-T14689-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T14689-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
BMS493 is an inverse pan-retinoic acid receptor (RAR) agonist. BMS493 also could prevent retinoic acid-induced differentiation. BMS493 increases nuclear corepressor interaction with RARs[1][2].
CAS:
215030-90-3
Formula:
C29H24O2
Molecular Weight:
404.509
Pathway:
Metabolism
Purity:
0.98
SMILES:
CC1(C)CC=C(C#Cc2ccccc2)c2cc(C=Cc3ccc(cc3)C(O)=O)ccc12
Target:
Retinoid Receptor
References
1. Elgamal RM, et al. BMS 493 Modulates Retinoic Acid-Induced Differentiation During Expansion of Human Hematopoietic Progenitor Cells for Islet Regeneration. Stem Cells Dev. 2018 Aug 1;27(15):1062-1075.
2. Yu Z, et al. Apoptosis induced by atRA in MEPM cells is mediated through activation of caspase and RAR. Toxicol Sci. 2006 Feb;89(2):504-9.