Valproic acid sodium salt
| Code | Size | Price |
|---|
| TAR-T1602-500mg | 500mg | £104.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T1602-1g | 1g | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Valproate Sodium is the sodium salt form of valproic acid with anti-epileptic activity. Valproate sodium is converted into its active form, valproate ion, in blood. Although the mechanism of action remains to be elucidated, valproate sodium increases concentrations of gamma-aminobutyric acid (GABA) in the brain, probably due to inhibition of the enzymes responsible for the catabolism of GABA. This potentiates the synaptic actions of GABA. Valproate sodium may also affect potassium channels, thereby creating a direct membrane-stabilizing effect.
CAS:
1069-66-5
Formula:
C8H15NaO2
Molecular Weight:
166.196
Pathway:
Autophagy; Stem Cells; Microbiology/Virology; Membrane transporter/Ion channel; Neuroscience; DNA Damage/DNA Repair; Chromatin/Epigenetic; Proteases/Proteasome
Purity:
0.99
SMILES:
[Na+].CCCC(CCC)C([O-])=O
Target:
Mitophagy; Gamma-secretase; HIV Protease; GABA Receptor; HDAC; Autophagy
References
1. Phiel CJ, et al. J Biol Chem, 2001, 276(39), 36734-36741.
2. G?ttlicher M, et al. EMBO J, 2001, 20(24), 6969-6978.