SCH28080

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TargetMol
Product Code: TAR-T16865
Supplier: TargetMol
CodeSizePrice
TAR-T16865-1mg1mg£108.00
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TAR-T16865-1mL1 mL * 10 mM (in DMSO)£157.00
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Quantity:
TAR-T16865-5mg5mg£160.00
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Quantity:
TAR-T16865-10mg10mg£203.00
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Quantity:
TAR-T16865-25mg25mg£295.00
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TAR-T16865-50mg50mg£405.00
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TAR-T16865-100mg100mg£547.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
SCH28080 inhibits gastric H+/K+-ATPase by K+-competitive binding (IC50: 20 nM in rabbit microsomal membranes).
CAS:
76081-98-6
Formula:
C17H15N3O
Molecular Weight:
277.327
Pathway:
Membrane transporter/Ion channel
Purity:
0.98
SMILES:
Cc1nc2c(OCc3ccccc3)cccn2c1CC#N
Target:
ATPase

References

1. Scott CK, et al. Studies on the mechanism of action of the gastric microsomal (H+ + K+)-ATPase inhibitors SCH 32651 and SCH 28080. Biochem Pharmacol. 1987 Jan 1;36(1):97-104. 2. Long JF, et al. Gastric antisecretory and cytoprotective activities of SCH 28080. J Pharmacol Exp Ther. 1983 Jul;226(1):114-20.