Pomalidomide-PEG4-C-COOH

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TargetMol
Product Code: TAR-T17325
Supplier: TargetMol
CodeSizePrice
TAR-T17325-1mg1mg£99.00
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TAR-T17325-5mg5mg£138.00
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TAR-T17325-1mL1 mL * 10 mM (in DMSO)£158.00
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TAR-T17325-10mg10mg£168.00
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TAR-T17325-25mg25mg£230.00
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TAR-T17325-50mg50mg£309.00
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Quantity:
TAR-T17325-100mg100mg£436.00
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TAR-T17325-200mg200mg£699.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
Pomalidomide-PEG4-C-COOH is a synthesized E3 ligase ligand-linker conjugate that combines the Pomalidomide-based cereblon ligand and 4-unit PEG linker used in PROTAC technology.
CAS:
2097938-44-6
Formula:
C23H29N3O10
Molecular Weight:
507.496
Pathway:
Others|PROTAC
Purity:
0.98
SMILES:
OC(=O)COCCOCCOCCOCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
Target:
Others|E3 Ligase Ligand-Linker Conjugate

References

1. Guangrong Zheng, et al. Compounds that induce degradation of anti-apoptotic bcl-2 family proteins and the uses thereof. WO2017184995A1.