Diglycyl-histidine

TargetMol
Product Code: TAR-T20382
Supplier: TargetMol
CodeSizePrice
TAR-T20382-100mg100mg£295.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T20382-500mg500mg£578.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Diglycyl-histidine is a tripeptide complexed with cupric ion designed to mimic specific Cu(II) transport site of ascorbate on albumin molecule.
CAS:
7451-76-5
Formula:
C10H15N5O4
Molecular Weight:
269.261
Purity:
0.98
SMILES:
NCC(=O)NCC(=O)N[C@@H](Cc1c[nH]cn1)C(O)=O

References

1. Hu X, Zhang Q, Wang W, Yuan Z, Zhu X, Chen B, Chen X. Tripeptide GGH as the Inhibitor of Copper-Amyloid-?-Mediated Redox Reaction and Toxicity. ACS Chem Neurosci. 2016 Sep 21;7(9):1255-63. doi: 10.1021/acschemneuro.6b00145. Epub 2016 Aug 3. PubMed PMID: 27433833. 2. Gerlich M, Neumann S. MetFusion: integration of compound identification strategies. J Mass Spectrom. 2013 Mar;48(3):291-8. doi: 10.1002/jms.3123. PubMed PMID: 23494783. 3. Joyner JC, Hodnick WF, Cowan AS, Tamuly D, Boyd R, Cowan JA. Antimicrobial metallopeptides with broad nuclease and ribonuclease activity. Chem Commun (Camb). 2013 Mar 14;49(21):2118-20. doi: 10.1039/c3cc38977d. Epub 2013 Feb 5. PubMed PMID: 23380915; PubMed Central PMCID: PMC3632407. 4. Gruchlik A, Jurzak M, Chodurek E, Dzierzewicz Z. Effect of Gly-Gly-His, Gly-His-Lys and their copper complexes on TNF-alpha-dependent IL-6 secretion in normal human dermal fibroblasts. Acta Pol Pharm. 2012 Nov-Dec;69(6):1303-6. PubMed PMID: 23285694.