BrBzGCp2
Code | Size | Price |
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TAR-T24598-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T24598-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
p-BrBzGSH(Cp)2 is a glyoxylase 1 inhibitor. In orthotopic mouse models, it acts by increasing DNA-AGEs, stimulating RAGE expression, and inhibiting brain tumor growth.
CAS:
166038-00-2
Formula:
C27H38BrN3O6S
Molecular Weight:
612.58
Purity:
0.98
SMILES:
NC(CCC(=O)NC(CSCc1ccc(Br)cc1)C(=O)NCC(=O)OC1CCCC1)C(=O)OC1CCCC1
References
1. Jandial R, Neman J, Lim PP, Tamae D, Kowolik CM, Wuenschell GE, Shuck SC, Ciminera AK, De Jesus LR, Ouyang C, Chen MY, Termini J. Inhibition of GLO1 in Glioblastoma Multiforme Increases DNA-AGEs, Stimulates RAGE Expression, and Inhibits Brain Tumor Growth in Orthotopic Mouse Models. Int J Mol Sci. 2018 Jan 30;19(2). pii: E406. doi: 10.3390/ijms19020406. PubMed PMID: 29385725.