NSC-668036
Code | Size | Price |
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TAR-T28211-5mg | 5mg | £390.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28211-50mg | 50mg | £1,299.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28211-100mg | 100mg | £1,942.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
NSC-668036 is an inhibitor of Dishevelled (Dvl) protein, a key protein in wnt signaling.
CAS:
144678-63-7
Formula:
C21H36N2O9
Molecular Weight:
460.524
Purity:
0.98
SMILES:
CC(C)C(O)C(=O)N([C@@H](C)C(=O)O[C@@H](C(C)C)C(O)=O)C(=O)[C@H](C)NC(=O)OC(C)(C)C
References
1. Wang C, Dai J, Sun Z, Shi C, Cao H, Chen X, Gu S, Li Z, Qian W, Han X. Targeted inhibition of disheveled PDZ domain via NSC668036 depresses fibrotic process. Exp Cell Res. 2015 Feb 1;331(1):115-22. doi: 10.1016/j.yexcr.2014.10.023. Epub 2014 Nov 5. PubMed PMID: 25445788.
2. Chen X, Deng Y. Simulations of a specific inhibitor of the dishevelled PDZ domain. J Mol Model. 2009 Jan;15(1):91-6. doi: 10.1007/s00894-008-0377-x. Epub 2008 Oct 25. PubMed PMID: 18953581.
3. Shan J, Shi DL, Wang J, Zheng J. Identification of a specific inhibitor of the dishevelled PDZ domain. Biochemistry. 2005 Nov 29;44(47):15495-503. PubMed PMID: 16300398.