TargetMol

Betulinic acid

Product Code:
 
TAR-T2830
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2830-50mg50mg£97.00
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TAR-T2830-100mg100mg£109.00
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TAR-T2830-1mL1 mL * 10 mM (in DMSO)£114.00
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TAR-T2830-500mg500mg£210.00
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This product comes from: United States.
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Further Information

Bioactivity:
Betulinic acid is a pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) which has antiretroviral, antimalarial, and anti-inflammatory properties, as well as a more recently discovered potential as an anticancer agent, by inhibition of topoisomerase.
CAS:
472-15-1
Formula:
C30H48O3
Molecular Weight:
456.711
Pathway:
DNA Damage/DNA Repair; Proteases/Proteasome; Microbiology/Virology; Metabolism; Apoptosis; NF-κb; Autophagy
Purity:
0.997
SMILES:
CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)C(O)=O
Target:
Apoptosis; Mitophagy; NF-κB; HIV Protease; Topoisomerase; Endogenous Metabolite; Aminopeptidase; Autophagy

References

1. Fujioka T, et al. J Nat Prod, 1994, 57(2), 243-247. 2. Melzig MF, et al. Planta Med, 1998, 64(7), 655-657. 3. Chowdhury AR, et al. Med Sci Monit, 2002, 8(7), BR254-265. 4. Chintharlapalli S, et al. Cancer Res, 2007, 67, 2816-2823. 6. Kalra J, et al. Betulinic acid alleviates dextran sulfate sodium-induced colitis and visceral pain in mice. Naunyn Schmiedebergs Arch Pharmacol. 2017 Dec 26. 7. Tangliang Zhao1*, Yi Bao1*,Xinxin Gan1, et al. DNA methylation-regulated QPCT promotes sunitinib resistance by increasing HRAS stability in renal cell carcinoma. Theranostics. 2019, Vol. 9, Issue 22