Glycidamide
| Code | Size | Price |
|---|
| TAR-T31954-100mg | 100mg | £409.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T31954-200mg | 200mg | £634.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Glycidamide is a carcinogen and metabolite of acrylamide that induces DNA adduct formation and mutations.
CAS:
5694-00-8
Formula:
C3H5NO2
Molecular Weight:
87.078
Purity:
0.98
SMILES:
NC(=O)C1CO1
References
1. Wang ET, Chen DY, Liu HY, Yan HY, Yuan Y. Protective effect of allicin against glycidamide-induced toxicity in male and female mice. Gen Physiol Biophys. 2015 Apr;34(2):177-87. doi: 10.4149/gpb_2014038. Epub 2015 Mar 2. PubMed PMID: 25730897.
2. Beland FA, Olson GR, Mendoza MC, Marques MM, Doerge DR. Carcinogenicity of glycidamide in B6C3F1 mice and F344/N rats from a two-year drinking water exposure. Food Chem Toxicol. 2015 Dec;86:104-15. doi: 10.1016/j.fct.2015.09.017. Epub 2015 Sep 30. PubMed PMID: 26429628; PubMed Central PMCID: PMC5066397.
3. Fennell TR, Snyder R, Hansen B, Friedman M. Dosimetry of Acrylamide and Glycidamide Over the Lifespan in a 2-Year Bioassay of Acrylamide in Wistar Han Rats. Toxicol Sci. 2015 Aug;146(2):386-94. doi: 10.1093/toxsci/kfv104. Epub 2015 Jul 3. PubMed PMID: 26141391; PubMed Central PMCID: PMC4517054.
4. Gutzkow KB, Duale N, Danielsen T, von Stedingk H, Shahzadi S, Instanes C, Olsen AK, Steffensen IL, Hofer T, T?rnqvist M, Brunborg G, Lindeman B. Enhanced susceptibility of obese mice to glycidamide-induced sperm chromatin damage without increased oxidative stress. Andrology. 2016 Nov;4(6):1102-1114. doi: 10.1111/andr.12233. Epub 2016 Aug 30. PubMed PMID: 27575329.