TargetMol

L-Phenylalanine

Product Code:
 
TAR-T3377
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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TAR-T3377-200mg200mg£104.00
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TAR-T3377-1g1g£111.00
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Further Information

Bioactivity:
Phenylalanine is an essential amino acid and the precursor of the amino acid tyrosine, acts as an antagonist at α2δ calcium channels.
CAS:
63-91-2
Formula:
C9H11NO2
Molecular Weight:
165.19
Pathway:
Membrane transporter/Ion channel; Metabolism; Neuroscience
Purity:
0.9949
SMILES:
c1ccc(cc1)C[C@@H](C(=O)O)N
Target:
Calcium Channel; Endogenous Metabolite; iGluR

References

Wu WB, et al. Enhancement of l-phenylalanine production in Escherichia coli by heterologous expression of Vitreoscilla hemoglobin. Biotechnol Appl Biochem. 2018 May;65(3):476-483. Glushakov,A.V.et al. Specific inhibition of N-methyl-D-aspartate receptor function in rat hippocampal neurons by L-phenylalanine at concentrations observed during phenylketonuria. Mol Psychiatry, 2002. 7(4): p. 359-67. Glushakov, A.V., et al., Long-term changes in glutamatergic synaptic transmission in phenylketonuria. Brain, 2005. 128(Pt 2): p. 300-7. Mortell, K.H., et al., Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels. Bioorg Med Chem Lett, 2006. 16(5): p. 1138-41 Glushakov, A.V., et al., L-phenylalanine selectively depresses currents at glutamatergic excitatory synapses. J Neurosci Res, 2003. 72(1): p. 116-24 Moller, H.E., et al., Brain imaging and proton magnetic resonance spectroscopy in patients with phenylketonuria. Pediatrics, 2003. 112(6 Pt 2): p. 1580-3.