AKT-IN-6

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TargetMol
Product Code: TAR-T36310
Supplier: TargetMol
CodeSizePrice
TAR-T36310-1mg1mg£103.00
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Quantity:
TAR-T36310-1mL1 mL * 10 mM (in DMSO)£148.00
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Quantity:
TAR-T36310-5mg5mg£148.00
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Quantity:
TAR-T36310-10mg10mg£209.00
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Quantity:
TAR-T36310-25mg25mg£349.00
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Quantity:
TAR-T36310-50mg50mg£550.00
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Quantity:
TAR-T36310-100mg100mg£711.00
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TAR-T36310-500mg500mg£1,396.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
AKT-IN-6 (Example 13) is a potent Akt inhibitor. AKT-IN-6 inhibits Akt1, Akt2 and Akt3 with IC50s < 500nM, respectively. (patent WO2013056015A1).
CAS:
1430056-54-4
Formula:
C22H20FN5O
Molecular Weight:
389.434
Pathway:
Cytoskeletal Signaling|PI3K/Akt/mTOR signaling
Purity:
0.98
SMILES:
Cn1ncc(C#N)c1-c1ccc2C(=O)N(Cc2c1)[C@H](CN)Cc1cccc(F)c1
Target:
Akt

References

Eva-Maria Cox , et al.AKT activity orchestrates marginal zone B cell development in mice and humans.Volume 42, Issue 4, 25 April 2023, 112378 Manning BD, et al. AKT/PKB signaling: navigating downstream. Cell. 2007;129(7):1261-1274.