4-hydroxyphenylacetic acid
| Code | Size | Price |
|---|
| TAR-T3743-100mg | 100mg | £103.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T3743-1mL | 1 mL * 10 mM (in DMSO) | £107.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T3743-200mg | 200mg | £117.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
4-hydroxyphenylacetic acid is a major microbiota-derived metabolite of polyphenols. 4-hydroxyphenylacetic acid is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2.
CAS:
156-38-7
Formula:
C8H8O3
Molecular Weight:
152.149
Pathway:
Metabolism; Immunology/Inflammation; oxidation-reduction
Purity:
0.991
SMILES:
OC(=O)Cc1ccc(O)cc1
Target:
Antioxidant; Nrf2; Endogenous Metabolite
References
An S, Yao Y, Wu J, et al.Gut-derived 4-hydroxyphenylacetic acid attenuates sepsis-induced acute kidney injury by upregulating ARC to inhibit necroptosis.Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease.2024, 1870(1): 166876.
Zhao H, et al. 4-Hydroxyphenylacetic Acid Prevents Acute APAP-Induced Liver Injury by Increasing Phase IIand Antioxidant Enzymes in Mice. Front Pharmacol. 2018 Jun 19;9:653.