Methyl-β-cyclodextrin
| Code | Size | Price |
|---|
| TAR-T4072-500mg | 500mg | £97.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T4072-1g | 1g | £104.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Methyl-β-cyclodextrin, a cyclic heptasaccharide, is an effective agent for the depletion of cholesterol from cells; also inhibits PEL cell growth with an IC50 of 3.33-4.23 mM.
CAS:
128446-36-6
Formula:
C54H94O35
Molecular Weight:
1303.311
Purity:
0.98
SMILES:
CO[C@H]1[C@H](O)[C@@H]2O[C@H]3O[C@H](CO)[C@@H](O[C@H]4O[C@H](CO)[C@@H](O[C@H]5O[C@H](CO)[C@@H](O[C@H]6O[C@H](CO)[C@@H](O[C@H]7O[C@H](CO)[C@@H](O[C@H]8O[C@H](CO)[C@@H](O[C@H]1O[C@@H]2CO)[C@@H](O)[C@@H]8OC)[C@@H](OC)[C@@H]7OC)[C@@H](OC)[C@@H]6OC)[C@@H](OC)[C@@H]5OC)[C@@H](OC)[C@@H]4OC)[C@@H](OC)[C@@H]3OC
References
Zhang Y, Xue W, Zhang W, et al. Histone methyltransferase G9a protects against acute liver injury through GSTP1. Cell Death & Differentiation. 2020, 27(4): 1243-1258
Lu J Y, Huang W T, Zhou K, et al. Microbial Lipopeptide Supramolecular Self?Assemblies as a Methuosis?Like Cell Death Inducer with In Vivo Antitumor Activity. Small. 2021: 2104034.
Gotoh, K., Kariya, R., Alam, M., Matsuda, K., Hattori, S., & Maeda, Y. et al. (2014). The antitumor effects of methyl-?-cyclodextrin against primary effusion lymphoma via the depletion of cholesterol from lipid rafts.?Biochemical And Biophysical Research Communications,?455(3-4), 285-289. doi: 10.1016/j.bbrc.2014.11.006
Li X, Tang H, Huang X, et al. Rigidity?Dependent Placental Cells Uptake of Silk?Based Microcapsules[J]. Macromolecular bioscience. 2019: 1900105.
Tiwari G, et al. Cyclodextrins in delivery systems: Applications. J Pharm Bioallied Sci. 2010 Apr;2(2):72-9.
Zhang Y, Xue W, Zhang W, et al. Histone methyltransferase G9a protects against acute liver injury through GSTP1. Cell Death & Differentiation. 2019: 1-16.
Li X, Tang H, Huang X, et al. Rigidity?Dependent Placental Cells Uptake of Silk?Based Microcapsules. Macromolecular bioscience. 2019: 1900105.
Zeng L, Liu H, Liu Z, et al.Defected lipid rafts suppress cavin1-dependent IFN-? signaling endosome in paroxysmal nocturnal hemoglobinuria.International Immunopharmacology.2023, 115: 109468.
Wang T, Wang L, Li W, et al.Fowl adenovirus serotype 4 enters leghorn male hepatocellular cells via the clathrin-mediated endocytosis pathway.Veterinary Research.2023, 54(1): 1-14.