L-Homocystine
| Code | Size | Price |
|---|
| TAR-T4877-100mg | 100mg | £116.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Homocystine is the double-bonded form of homocysteine, but it occurs only transiently before being converted to the harmless cystathionine via a vitamin B6-dependent enzyme. Increasing evidence supports a role for an elevation of homocysteine in schizophrenia. It has been demonstrated that neural tube defects are related to a genetic defect in homocysteine metabolism. Sufficient intake of folic acid is believed to reduce this risk by enhancing methylation of homocysteine and its conversion to methionine, thereby compensating for this genetic defect (homocystinuria). Plasma homocysteine levels are elevated when folate levels are in the lower half of the normal range.
CAS:
626-72-2
Formula:
C8H16N2O4S2
Molecular Weight:
268.35
Pathway:
Metabolism
Purity:
0.9965
SMILES:
N[C@@H](C(O)=O)CCSSCC[C@H](C(O)=O)N
Target:
Endogenous Metabolite
References
Carson N A J , Dent C E , Field C M B , et al. Homocystinuria: Clinical and pathological review of ten cases[J]. Journal of Pediatrics, 1965, 66(3).
Bhardwaj P, Sharma R, Sharma M. Homocystinuria: A rare condition presenting as stroke and megaloblastic anemia.[J]. Journal of Pediatric Neurosciences, 2010, 5(2):129-131.
Kerrin D , Murdoch E D , Livingston J , et al. Homocystinuria presenting with sagittal sinus thrombosis in infancy.[J]. Journal of Child Neurology, 1996, 11(1):70-1.