3-Methyl-2-oxobutanoic acid

TargetMol
Product Code: TAR-T5232
Supplier: TargetMol
CodeSizePrice
TAR-T5232-1mL1 mL * 10 mM (in DMSO)£107.00
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Quantity:
TAR-T5232-100mg100mg£117.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
alpha-Ketoisovaleric acid is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids. alpha-Ketoisovaleric acid is a neurotoxin, an acidogen, and a metabotoxin. A neurotoxin causes damage to nerve cells and nerve tissues. alpha-Ketoisovaleric acid is a keto-acid, which is a subclass of organic acids. Abnormally high levels of organic acids in the blood (organic acidemia), urine (organic aciduria), the brain, and other tissues lead to general metabolic acidosis.
CAS:
759-05-7
Formula:
C5H8O3
Molecular Weight:
116.116
Pathway:
; Metabolism
Purity:
0.95
SMILES:
CC(C)C(=O)C(O)=O
Target:
Endogenous Metabolite

References

Yudkoff M, et al. Brain amino acid requirements and toxicity: the example of leucine. J Nutr. 2005 Jun;135(6 Suppl):1531S-8S.