Pantoprazole sodium
Code | Size | Price |
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TAR-T6929-1mL | 1 mL * 10 mM (in DMSO) | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6929-100mg | 100mg | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6929-200mg | 200mg | £125.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Pantoprazole Sodium is the sodium salt form of a substituted benzimidazole with proton pump inhibitor activity. Pantoprazole is a lipophilic, weak base that crosses the parietal cell membrane and enters the acidic parietal cell canaliculus where it becomes protonated, producing the active metabolite sulfenamide, which forms an irreversible covalent bond with two sites of the H+/K+-ATPase enzyme located on the gastric parietal cell, thereby inhibiting both basal and stimulated gastric acid production.
CAS:
138786-67-1
Formula:
C16H14F2N3NaO4S
Molecular Weight:
405.35
Pathway:
Autophagy; Angiogenesis; Apoptosis; Membrane transporter/Ion channel; Chromatin/Epigenetic;
Purity:
0.991
SMILES:
[Na+].COc1ccnc(CS(=O)c2nc3cc(OC(F)F)ccc3[n-]2)c1OC
Target:
Apoptosis; Proton pump; HIF; Autophagy
References
Y Wu, et al. Chinese Journal of Gastroenterology. 2010, 15(4):205-208.
Shen Y, et al. Neoplasma. 2012, 59(2):142-149.
Yeo M, et al. Clin Cancer Res. 2004, 10(24):8687-8696.
Shen Y, et al. Oncol Lett. 2016, 11(1):717-722.