2,4-Diamino-6-hydroxypyrimidine
| Code | Size | Price |
|---|
| TAR-T7461-100mg | 100mg | £103.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T7461-1mL | 1 mL * 10 mM (in DMSO) | £107.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
2,4-Diamino-6-hydroxypyrimidine (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis
CAS:
56-06-4
Formula:
C4H6N4O
Molecular Weight:
126.119
Pathway:
NF-κb; Metabolism; Immunology/Inflammation
Purity:
0.9926
SMILES:
Nc1cc(O)nc(N)n1
Target:
Reactive Oxygen Species; NO Synthase
References
Werner-Felmayer G , Werner E R , Fuchs D , et al. Pteridine biosynthesis in human endothelial cells. Impact on nitric oxide-mediated formation of cyclic GMP[J]. Journal of Biological Chemistry, 1993, 268(3):1842-1846.
Sung Y J , Hotchkiss J H , Dieteri R R . 2,4-diamino-6-hydroxypyrimidine, an inhibitor of GTP cyclohydrolase I, suppresses nitric oxide production by chicken macrophages[J]. International Journal of Immunopharmacology, 1994, 16(2):101-108.