TargetMol

2,4-Diamino-6-hydroxypyrimidine

Product Code:
 
TAR-T7461
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T7461-100mg100mg£103.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T7461-1mL1 mL * 10 mM (in DMSO)£107.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
2,4-Diamino-6-hydroxypyrimidine (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis
CAS:
56-06-4
Formula:
C4H6N4O
Molecular Weight:
126.119
Pathway:
NF-κb; Metabolism; Immunology/Inflammation
Purity:
0.9926
SMILES:
Nc1cc(O)nc(N)n1
Target:
Reactive Oxygen Species; NO Synthase

References

Werner-Felmayer G , Werner E R , Fuchs D , et al. Pteridine biosynthesis in human endothelial cells. Impact on nitric oxide-mediated formation of cyclic GMP[J]. Journal of Biological Chemistry, 1993, 268(3):1842-1846. Sung Y J , Hotchkiss J H , Dieteri R R . 2,4-diamino-6-hydroxypyrimidine, an inhibitor of GTP cyclohydrolase I, suppresses nitric oxide production by chicken macrophages[J]. International Journal of Immunopharmacology, 1994, 16(2):101-108.