Fingolimod
Code | Size | Price |
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TAR-T7939-100mg | 100mg | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T7939-1mL | 1 mL * 10 mM (in DMSO) | £113.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T7939-500mg | 500mg | £172.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T7939-1g | 1g | £197.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Fingolimod is an antagonist of sphingosine 1-phosphate (S1P) (IC50 of 0.033 nM in K562 and NK cells).
CAS:
162359-55-9
Formula:
C19H33NO2
Molecular Weight:
307.478
Pathway:
Cytoskeletal Signaling; GPCR/G Protein
Purity:
0.9976
SMILES:
CCCCCCCCc1ccc(CCC(N)(CO)CO)cc1
Target:
S1P Receptor; PAK; LPL Receptor
References
Wang X, Li X, Wang J, et al. SMGL-1/NBAS acts as a RAB-8 GEF to regulate unconventional protein secretion. Journal of Cell Biology. 2022, 221(7): e202111125
Zhang T, Wang Y, Li Q, et al. Mesenchymal stromal cells equipped by IFN? empower T cells with potent anti-tumor immunity. Oncogene. 2022: 1-16.
Szepanowski, Fabian, Derksen, Angelika, Steiner, Irina,et al. Fingolimod promotes peripheral nerve regeneration via modulation of lysophospholipid signaling[J]. Journal of Neuroinflammation, 13(1):143.
Amelioration of colitis through blocking lymphocytes entry to Peyer's patches by sphingosine?1?phosphate lyase inhibitor[J]. Journal of Gastroenterology & Hepatology, 2018, 33(9).