6-AZATHYMINE

TargetMol
Product Code: TAR-T8648
Supplier: TargetMol
CodeSizePrice
TAR-T8648-1mL1 mL * 10 mM (in DMSO)£107.00
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Quantity:
TAR-T8648-100mg100mg£121.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T8648-500mg500mg£172.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
6-azathymine is a potent inhibitors of D-3-aminoisobutyrate-pyruvate aminotransferase. 6-Azauracil acted as a competitive inhibitor with respect to beta-alanine, and was an uncompetitive inhibitor with respect to pyruvic acid with a Ki of approximately 8.9 mM.
CAS:
932-53-6
Formula:
C4H5N3O2
Molecular Weight:
127.103
Pathway:
Cell Cycle/Checkpoint; Microbiology/Virology; DNA Damage/DNA Repair
Purity:
1
SMILES:
Cc1n[nH]c(=O)[nH]c1=O
Target:
Nucleoside Antimetabolite/Analog; Influenza Virus; DNA/RNA Synthesis; Antibacterial

References

N Tamaki, et al. Purification, Characterization and Inhibition of D-3-aminoisobutyrate Aminotransferase From the Rat Liver. Eur J Biochem. 1990 Apr 20;189(1):39-45. R A GAITO, et al. Studies on the Metabolism of Thymine and 6-azathymine. Biochem Pharmacol. Apr-May 1962;11:323-36.