DPH

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TargetMol
Product Code: TAR-T15164
Supplier: TargetMol
CodeSizePrice
TAR-T15164-1mg1mg£97.00
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TAR-T15164-2mg2mg£107.00
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TAR-T15164-5mg5mg£131.00
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TAR-T15164-10mg10mg£166.00
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TAR-T15164-1mL1 mL * 10 mM (in DMSO)£174.00
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TAR-T15164-25mg25mg£269.00
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TAR-T15164-50mg50mg£462.00
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TAR-T15164-100mg100mg£603.00
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TAR-T15164-200mg200mg£847.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
DPH is a potent cell-permeable activator of c-Abl. It shows potent enzymatic and cellular activity in stimulating c-Abl activation.
CAS:
484049-04-9
Formula:
C18H13FN4O2
Molecular Weight:
336.326
Pathway:
Cytoskeletal Signaling|Tyrosine Kinase/Adaptors|Angiogenesis
Purity:
0.98
SMILES:
Fc1ccc(cc1)-c1nn(cc1C1NC(=O)NC1=O)-c1ccccc1
Target:
Bcr-Abl

References

Shapiro LP, et al. Corticosteroid-induced dendrite loss and behavioral deficiencies can be blocked by activation of Abl2/Arg kinase. Mol Cell Neurosci. 2017 Oct 26;85:226-234. Yang J, et al. Discovery and characterization of a cell-permeable, small-molecule c-Abl kinase activator that binds to the myristoyl binding site. Chem Biol. 2011 Feb 25;18(2):177-86