Amino-PEG10-acid

TargetMol
Product Code: TAR-T20090
Supplier: TargetMol
CodeSizePrice
TAR-T20090-200mg200mg£356.00
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TAR-T20090-500mg500mg£657.00
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Quantity:
TAR-T20090-1g1g£902.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Amino-PEG10-acid is a PEG derivative containing an amino group with a terminal carboxylic acid. PEG Linkers may be useful in the development of antibody-drug conjugates and drug delivery methods. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators to form a stable amide bond.
CAS:
196936-04-6
Formula:
C23H47NO12
Molecular Weight:
529.62
Purity:
0.98
SMILES:
OC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN)=O

References

1. Pignatello R, Impallomeni G, Pistar? V, Cupri S, Graziano AC, Cardile V, Ballistreri A. New amphiphilic derivatives of poly(ethylene glycol) (PEG) as surface modifiers of colloidal drug carriers. III. Lipoamino acid conjugates with carboxy- and amino-PEG(5000) polymers. Mater Sci Eng C Mater Biol Appl. 2015 Jan;46:470-81. doi: 10.1016/j.msec.2014.10.054. Epub 2014 Oct 23. PubMed PMID: 25492012. 2. Rubio-Garcia J, Coppel Y, Lecante P, Mingotaud C, Chaudret B, Gauffre F, Kahn ML. One-step synthesis of metallic and metal oxide nanoparticles using amino-PEG oligomers as multi-purpose ligands: size and shape control, and quasi-universal solvent dispersibility. Chem Commun (Camb). 2011 Jan 21;47(3):988-90. doi: 10.1039/c0cc02615h. Epub 2010 Nov 26. PubMed PMID: 21113535. 3. Kitagawa F, Kubota K, Sueyoshi K, Otsuka K. One-step preparation of amino-PEG modified poly(methyl methacrylate) microchips for electrophoretic separation of biomolecules. J Pharm Biomed Anal. 2010 Dec 15;53(5):1272-7. doi: 10.1016/j.jpba.2010.07.008. Epub 2010 Aug 1. PubMed PMID: 20678876. 4. Yoshimoto K, Hoshino Y, Ishii T, Nagasaki Y. Binding enhancement of antigen-functionalized PEGylated gold nanoparticles onto antibody-immobilized surface by increasing the functionalized antigen using alpha-sulfanyl-omega-amino-PEG. Chem Commun (Camb). 2008 Nov 14;(42):5369-71. doi: 10.1039/b811818c. Epub 2008 Sep 16. PubMed PMID: 18985213.