Sancycline HCl
| Code | Size | Price |
|---|
| TAR-T3052L-200mg | 200mg | £1,119.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Sancycline is a semi-synthetic tetracycline antibiotic that is more active than tetracycline against 339 strains of anaerobic bacteria (MIC90s = 1 and 32 μg/ml, respectively).
CAS:
6625-20-3
Formula:
C21H23ClN2O7
Molecular Weight:
450.87
Purity:
0.98
SMILES:
Cl.[H][C@@]12Cc3cccc(O)c3C(=O)C1=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@]1([H])C2
References
1. Yang X, Zhao L, Almasy L, Garamus VM, Zou A, Willumeit R, Fan S. Preparation and characterization of 4-dedimethylamino sancycline (CMT-3) loaded nanostructured lipid carrier (CMT-3/NLC) formulations. Int J Pharm. 2013 Jun 25;450(1-2):225-34. doi: 10.1016/j.ijpharm.2013.04.021. Epub 2013 Apr 20. PubMed PMID: 23608200.
2. Pinsuwan S, Alvarez-N??ez FA, Tabibi SE, Yalkowsky SH. Spectrophotometric determination of acidity constants of 4-dedimethylamino sancycline (Col-3), a new antitumor drug. J Pharm Sci. 1999 May;88(5):535-7. PubMed PMID: 10229645.
3. Hasan T, Goldman RA, Cooperman BS. Photoaffinity labeling of the tetracycline binding site of the Escherichia coli ribosome. The uses of a high intensity light source and of radioactive sancycline derivatives. Biochem Pharmacol. 1985 Apr 1;34(7):1065-71. PubMed PMID: 3885955.
4. Pinsuwan S, Alvarez-N??ez FA, Tabibi ES, Yalkowsky SH. Degradation kinetics of 4-dedimethylamino sancycline, a new anti-tumor agent, in aqueous solutions. Int J Pharm. 1999 Apr 20;181(1):31-40. PubMed PMID: 10370200.