Termitomycamide B

TargetMol
Product Code: TAR-T36328
Supplier: TargetMol
CodeSizePrice
TAR-T36328-200mg200mg£1,046.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Endoplasmic reticulum (ER) stress, caused by accumulation of misfolded proteins and a disruption of calcium homeostasis, has been linked to several neuronal diseases including, Parkinson's, Alzheimer's, and prion diseases. A screen for protective activity against ER stress-dependent cell death identified termitomycamides, extracts from the fruiting bodies of T. titanicus, a notably large edible mushroom that is cultivated symbiotically in the nests of termites Termitomycamide B is a fatty acid isolated from T. titanicus that at a dose of 0.1 μg/ml protects against ER stress-dependent cell death in Neuro2a cells induced by tunicamycin.
CAS:
1254277-89-8
Formula:
C28H40N2O2
Molecular Weight:
436.64
Purity:
0.98
SMILES:
CCCCCC=C/CC=C/CCCCCCCC(=O)NCC(=O)c1cc2ccccc2[nH]1