G-418 disulfate
| Code | Size | Price |
|---|
| TAR-T6512-500mg | 500mg | £104.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T6512-1g | 1g | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
G-418 (disulfate) is an aminoglycoside antibiotic, which blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.
CAS:
108321-42-2
Formula:
C20H44N4O18S2
Molecular Weight:
692.7
Pathway:
Microbiology/Virology
Purity:
0.999
SMILES:
OS(O)(=O)=O.OS(O)(=O)=O.CN[C@@H]1[C@@H](O)[C@@H](O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H]([C@@H](C)O)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O)OC[C@]1(C)O
Target:
Antibacterial; Antibiotic
References
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Yan R, Xie E, Li Y, et al. The structure of erastin-bound xCT?4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis. Cell Research. 2022-32?7?P1-4
Wang W, Zhang M, Huang Z, et al. Knockdown of CXCL5 inhibits the invasion, metastasis and stemness of bladder cancer lung metastatic cells by downregulating CD44. Anti-Cancer Drugs. 2022, 33(1): e103-e112.
Li Y, et al. World J Gastroenterol, 2003, 9(10), 2174-2177.
Davies J, et al. Am J Trop Med Hyg, 1980, 29(5 Suppl), 1089-1092
Shao C S, Zhou X H, Miao Y H, et al. In-situ observation of mitochondrial biogenesis as the early event of apoptosis[J]. bioRxiv. 2021: 2020.08. 23.263152.
Shao C S, Zhou X H, Miao Y H, et al. In situ observation of mitochondrial biogenesis as the early event of apoptosis. Iscience. 2021, 24(9): 103038
Wang W, Zhang M, Huang Z, et al. Knockdown of CXCL5 inhibits the invasion, metastasis and stemness of bladder cancer lung metastatic cells by downregulating CD44. Anti-Cancer Drugs. 2022, 33(1): e103-e112.
Shao C S, Zhou X H, Miao Y H, et al. In-situ observation of mitochondrial biogenesis as the early event of apoptosis. Iscience. 2021, 24(9): 103038.