Alagebrium chloride

TargetMol
Product Code: TAR-T7143
Supplier: TargetMol
CodeSizePrice
TAR-T7143-200mg200mg£103.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T7143-1mL1 mL * 10 mM (in DMSO)£107.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Alagebrium Chloride is an advanced glycation end product (AGE) inhibitor, and has proven effective in reducing systolic blood pressure and providing therapeutic benefit for patients with diastolic
CAS:
341028-37-3
Formula:
C13H14ClNOS
Molecular Weight:
267.77
Pathway:
; Metabolism
Purity:
0.98
SMILES:
[Cl-].Cc1sc[n+](CC(=O)c2ccccc2)c1C
Target:
Endogenous Metabolite

References

Jin-Bae K , Byeong-Wook S , Sungha P , et al. Alagebrium Chloride, a Novel Advanced Glycation End-Product Cross Linkage Breaker, Inhibits Neointimal Proliferation in a Diabetic Rat Carotid Balloon Injury Model[J]. Korean Circulation Journal, 2010, 40(10):520-. Watson A M D , Gray S P , Jiaze L , et al. Alagebrium Reduces Glomerular Fibrogenesis and Inflammation Beyond Preventing RAGE Activation in Diabetic Apolipoprotein E Knockout Mice[J]. Diabetes, 2012, 61(8):2105-2113.