Edaravone
| Code | Size | Price |
|---|
| TAR-T0407-500mg | 500mg | £105.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T0407-1mL | 1 mL * 10 mM (in DMSO) | £109.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Edaravone(MCI-186) is a potent new free radical scavenger used for the therapy of patients with acute brain infarction.
CAS:
89-25-8
Formula:
C10H10N2O
Molecular Weight:
174.203
Pathway:
oxidation-reduction; Proteases/Proteasome; Apoptosis
Purity:
0.9944
SMILES:
CC1=NN(C(=O)C1)c1ccccc1
Target:
Apoptosis; MMP; Free radical scavengers
References
1. Yoshida H, et al. CNS Drug Rev, 2006, 12(1), 9-20.
2. Zhang N, et al. Stroke, 2005, 36(10), 2220-2225.
3. Doi K, et al. Kidney Int, 2004, 65(5), 1714-1723.
4. Amemiya S, et al. Eur J Pharmacol, 2005, 516(2), 125-130.
6. Bai X, et al. Protective Effect of Edaravone on Glutamate-Induced Neurotoxicity in Spiral Ganglion Neurons. Neural Plast. 2016;2016:4034218. Epub 2016 Nov 10.
7. Wang F, Li R, Tu P, et al. Total glycosides of Cistanche deserticola promote neurological function recovery by inducing neurovascular regeneration via Nrf-2/Keap-1 pathway in MCAO/R rats[J]. Frontiers in Pharmacology. 2020, 11.