Ketanserin tartrate
| Code | Size | Price |
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| TAR-T1066L-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T1066L-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Ketanserin tartrate is an antagonist of 5-HT2A receptor and TRPV1 receptor. It also a potential α1-adrenergic receptor antagonist used to treat hypertension.
CAS:
83846-83-7
Formula:
C26H28FN3O9
Molecular Weight:
545.52
Purity:
0.98
SMILES:
O[C@H]([C@@H](O)C(O)=O)C(O)=O.Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1
References
1. Tu X, Zuo J, Hu K, Kang J, Mei Y, Wang N. Effect of Systemic Application of 5-Hydroxytryptamine on Hypoglossal Nerve Discharge in Anesthetized Rats. J Mol Neurosci. 2015 Nov;57(3):435-45. doi: 10.1007/s12031-015-0590-x. Epub 2015 Jun 16. PubMed PMID: 26076739.
2. Suzukawa M, Nakamura H. Effects of ketanserin tartrate on 3-hydroxy, 3-methylglutaryl coenzyme A reductase activity in cultured human skin fibroblasts. Cardiovasc Drugs Ther. 1990 Jan;4 Suppl 1:69-72. PubMed PMID: 1981023.
3. Nakamura H, Hirata F, Yasugi T, Mizuno M, Saito E, Ishikawa T, Tada N, Nakaya N, Homma Y, Takeuchi I. Effects of ketanserin tartrate on serum lipids in patients with essential hypertension. Drugs. 1988;36 Suppl 1:25-34. PubMed PMID: 3071460.
4. Suzukawa M, Nakamura H. Effect of ketanserin tartrate on HMG CoA reductase and LDL receptor activity in cultured human skin fibroblasts. Eur J Clin Pharmacol. 1990;39(3):217-20. PubMed PMID: 2257855.