Perphenazine
| Code | Size | Price |
|---|
| TAR-T1090-50mg | 50mg | £94.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T1090-1mL | 1 mL * 10 mM (in DMSO) | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Perphenazine is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.
CAS:
58-39-9
Formula:
C21H26ClN3OS
Molecular Weight:
403.97
Pathway:
Immunology/Inflammation; GPCR/G Protein; Neuroscience
Purity:
0.9963
SMILES:
OCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1
Target:
CaMK; Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; Histamine Receptor
References
1. Howard S. Smith, et al. Annals od palliative medicine. 2012, 1(2):137-142.
2. Ozdemir E, et al. Bosn J Basic Med Sci. 2013, 13(2):119-25.
3. Kate?ina Fialov?, et al. Acta Vet. Brno. 2011, 80: 87-92.
4. Seokheon Hong, et al. Animal Cells and Systems. 2012, 16(1):20-26.
5. Otrba M , Komider L . In vitro anticancer activity of fluphenazine, perphenazine and prochlorperazine. A review[J]. Journal of Applied Toxicology, 2020.
6. Bowden G D, Land K M, O'Connor R M, et al. High-throughput screen of drug repurposing library identifies inhibitors of Sarcocystis neurona growth[J]. International Journal for Parasitology: Drugs and Drug Resistance. 2018 Apr?8(1): 137-144.
7. Dong L, Shen S, Chen W, et al. Discovery of Novel Inhibitors Targeting Human O-GlcNAcase: Docking-Based Virtual Screening, Biological Evaluation, Structural Modification, and Molecular Dynamics Simulation[J]. Journal of chemical information and modeling. 2019, 59(10): 4374-4382.