Trimethoprim
| Code | Size | Price |
|---|
| TAR-T1153-500mg | 500mg | £107.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Trimethoprim is a Dihydrofolate Reductase Inhibitor Antibacterial. The mechanism of action of trimethoprim is as a Dihydrofolate Reductase Inhibitor, and Cytochrome P450 2C8 Inhibitor, and Organic Cation Transporter 2 Inhibitor.
CAS:
738-70-5
Formula:
C14H18N4O3
Molecular Weight:
290.323
Pathway:
DNA Damage/DNA Repair; Microbiology/Virology; Cell Cycle/Checkpoint; Metabolism
Purity:
0.9988
SMILES:
COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC
Target:
DHFR; DNA/RNA Synthesis; Antifolate; Antibacterial; Antibiotic
References
1. Vouloumanou EK, et al. Int J Antimicrob Agents, 2011, 38(3), 197-216.
2. Cribb AE, et al. Adverse Drug React Toxicol Rev, 1996, 15(1), 9-50.