MRS1845
| Code | Size | Price |
|---|
| TAR-T12108-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T12108-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
MRS1845 is a selective inhibitor of store-operated calcium (SOC) channel (IC50 of 1.7 μM).
CAS:
544478-19-5
Formula:
C21H22N2O6
Molecular Weight:
398.415
Pathway:
Membrane transporter/Ion channel; Metabolism
Purity:
0.98
SMILES:
CCOC(=O)C1=C(C)N(CC#C)C(C)=C(C1c1cccc(c1)[N+]([O-])=O)C(=O)OC
Target:
Calcium Channel
References
1. Harper JL, et al. Dihydropyridines as inhibitors of capacitative calcium entry in leukemic HL-60 cells. Biochem Pharmacol. 2003 Feb 1;65(3):329-38.
2. Ma K, et al. Phosphate-induced ORAI1 expression and store-operated Ca
3. Abdelazeem KNM, et al. Upregulation of Orai1 and STIM1 expression as well as store-operated Ca