Nicardipine hydrochloride

TargetMol
Product Code: TAR-T1215
Supplier: TargetMol
CodeSizePrice
TAR-T1215-500mg500mg£103.00
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Quantity:
TAR-T1215-1mL1 mL * 10 mM (in DMSO)£107.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T1215-1g1g£109.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Nicardipine Hydrochloride is the hydrochloride salt form of nicardipine, a synthetic derivative of nitrophenyl-pyridine and potent calcium channel blocker, Nicardipine (Nifedipine Family) blocks calcium ions from certain cell walls and inhibits contraction of coronary and peripheral arteries, resulting in lowered oxygen requirements for heart muscle and decreased arterial contraction and spasm. It is used clinically as a cerebral and coronary vasodilator.
CAS:
54527-84-3
Formula:
C26H30ClN3O6
Molecular Weight:
515.99
Pathway:
Membrane transporter/Ion channel; Neuroscience; Metabolism; Autophagy; GPCR/G Protein
Purity:
0.9987
SMILES:
Cl.COC(=O)C1=C(C)NC(C)=C(C1c1cccc(c1)[N+]([O-])=O)C(=O)OCCN(C)Cc1ccccc1
Target:
Calcium Channel; Adrenergic Receptor; AChR; Autophagy

References

1. Harino S, et al. Invest Ophthalmol Vis Sci, 1992, 33(10), 2885-2890. 2. Amenta F, et al. J Hypertens Suppl, 1996, 14(3), S29-35. 3. Willis AL, et al. Arteriosclerosis, 1985, 5(3), 250-255. 4. Gasior M, et al. J Neural Transm, 1996, 103(7), 819-831.