Hydroxocobalamin monohydrochloride
| Code | Size | Price |
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| TAR-T13731-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| TAR-T13731-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Hydroxocobalamin monohydrochloride is an injectable naturally occurring form of vitamin B12. It is used as a dietary supplement in the treatment of vitamin B12 deficiency including pernicious anemia.
CAS:
59461-30-2
Formula:
C62H90ClCoN13O15P
Molecular Weight:
1382.82
Purity:
0.98
SMILES:
CC12[N]([Co+3]34([N]5=CN(C(OC(CO)C6OP7([O-])=O)C6O)C8=C5C=C(C)C(C)=C8)([OH-])[N-]9C2C(CC(N)=O)C(C)(CCC(NCC(C)O7)=O)C9=C(C)C(C(CCC(N)=O)C%10(C)C)=[N]3C%10=CC%11=[N]4C(C(CC(N)=O)(C)C%11CCC(N)=O)=C%12C)=C%12C(CCC(N)=O)C1(C)CC(N)=O.Cl[H]
References
1. Cheungpasitporn W, et al. High-dose hydroxocobalamin for vasoplegic syndrome causing false blood leak alarm. Clin Kidney J. 2017 Jun;10(3):357-362.
2. Wang H, et al. Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency. Cochrane Database Syst Rev. 2018 Mar 15;3:CD004655.
3. Greenberg SS, et al. Hydroxocobalamin (vitamin B12a) prevents and reverses endotoxin-induced hypotension and mortality in rodents: role of nitric oxide. J Pharmacol Exp Ther. 1995 Apr;273(1):257-65.
4. Truong DH, et al. Prevention of hydrogen sulfide (H2S)-induced mouse lethality and cytotoxicity by hydroxocobalamin (vitamin B(12a)). Toxicology. 2007 Dec 5;242(1-3):16-22.