Amlodipine
Code | Size | Price |
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TAR-T1385-500mg | 500mg | £107.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T1385-1mL | 1 mL * 10 mM (in DMSO) | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T1385-1g | 1g | £128.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Amlodipine is a synthetic dihydropyridine and a calcium channel blocker with antihypertensive and antianginal properties.
CAS:
88150-42-9
Formula:
C20H25ClN2O5
Molecular Weight:
408.88
Pathway:
Membrane transporter/Ion channel; Metabolism
Purity:
0.9985
SMILES:
CCOC(=O)C1=C(COCCN)NC(C)=C(C1c1ccccc1Cl)C(=O)OC
Target:
Calcium Channel
References
1. Zhang X, et al. Circulation, 1998, 97(6), 576-580.
2. Mason RP, et al. J Mol Cell Cardiol, 1999, 31(1), 275-281.
3. Nussberger J, et al. Hypertension, 2008, 51(5), 1306-1311.
4. Mason RP, et al. J Neurochem, 1999, 72(4), 1448-1456.
5. Sharifi AM, et al. J Hypertens, 1998, 16(4), 457-466.
6. Pan X, Li R, Guo H, et al. Dihydropyridine Calcium Channel Blockers Suppress the Transcription of PD-L1 by Inhibiting the Activation of STAT1[J]. Frontiers in Pharmacology. 2021, 11: 2233.