Amoxapine
| Code | Size | Price |
|---|
| TAR-T1568-1mL | 1 mL * 10 mM (in DMSO) | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T1568-500mg | 500mg | £122.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Amoxapine exerts its antidepressant effect by inhibiting the re-uptake of norepinephrine and, to a lesser degree, of serotonin, at adrenergic nerve endings and blocks the response of dopamine receptors to dopamine. Amoxapine is a tricyclic antidepressant of the dibenzoxazepine class. This drug is used to treat symptoms of depression and may cause tardive dyskinesia. Amoxapine also binds to alpha-adrenergic, histaminergic, and cholinergic receptors which accounts for many of the side effects seen with this agent.
CAS:
14028-44-5
Formula:
C17H16ClN3O
Molecular Weight:
313.79
Pathway:
Neuroscience
Purity:
0.9884
SMILES:
Clc1ccc2Oc3ccccc3N=C(N3CCNCC3)c2c1
Target:
GlyT
References
1. N??ez E, et al. Br J Pharmacol. 2000 Jan;129(1):200-6.
2. Obers S, et al. Naunyn Schmiedebergs Arch Pharmacol, 2010, 381(5), 385-400.
3. Hamon M, et al. Neuropharmacology, 1987, 26(6), 531-539.
4. Maudhuit C, et al. Neuropharmacology, 1994, 33(8), 12017-1025.
5. Greenblatt EN, et al. Arch Int Pharmacodyn Ther, 1978, 233(1), 107-135.