Lanoconazole
| Code | Size | Price |
|---|
| TAR-T15708-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T15708-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Lanoconazole is an orally active imidazole antifungal agent that displays a broad spectrum of activity against fungi in vitro and in vivo. Lanoconazole interferes with ergosterol biosynthesis by inhibiting sterol 14-alpha demethylase and blocking fungal membrane ergosterol biosynthesis.
CAS:
101530-10-3
Formula:
C14H10ClN3S2
Molecular Weight:
319.83
Pathway:
Microbiology/Virology
Purity:
0.98
SMILES:
Clc1ccccc1C1CSC(S1)=C(C#N)n1ccnc1
Target:
Antifungal
References
1. Shokoohi GR, et al. In?Vitro?Activities?of?Luliconazole,?Lanoconazole, and?Efinaconazole?Compared?with Those of?Five?Antifungal?Drugs?against?Melanized?Fungi?and?Relatives.Antimicrob Agents Chemother.?2017 Oct 24;61(11). pii: e00635-17.
2. Nakamura A, et al. Anti-inflammatory?effect?of?lanoconazole?on?12-O-tetradecanoylphorbol-13-acetate- and?2,4,6-trinitrophenyl?chloride-induced?skin?inflammation?in?mice.Mycoses.?2020 Feb;63(2):189-196.
3. Furukawa K, et al. Lanoconazole, a new imidazole antimycotic compound, protects MAIDS?mice?against encephalitis caused by Cryptococcus neoformans.J Antimicrob Chemother.?2000 Sep;46(3):443-50.