Glibenclamide
| Code | Size | Price |
|---|
| TAR-T1634-500mg | 500mg | £107.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T1634-1mL | 1 mL * 10 mM (in DMSO) | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T1634-1g | 1g | £113.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Glyburide is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.
CAS:
10238-21-8
Formula:
C23H28ClN3O5S
Molecular Weight:
494
Pathway:
Neuroscience; Autophagy; Metabolism; Membrane transporter/Ion channel
Purity:
0.9977
SMILES:
COc1ccc(Cl)cc1C(=O)NCCc1ccc(cc1)S(=O)(=O)NC(=O)NC1CCCCC1
Target:
Potassium Channel; Mitochondrial Metabolism; CFTR; P-gp; Autophagy
References
1. Winquist RJ, et al. J Pharmacol Exp Ther,1989, 248(1), 149-156.
2. Nieland TJ, et al. J Lipid Res,2004, 45(7), 1256-1265.
3. Brady PA, et al. Eur J Pharmacol,1996, 308(3), 343-349.
4. Meisheri KD, et al. J Vasc Res,1993, 30(1), 2-12.
5. Clark MA, et al. J Pharmacol Exp Ther,1993, 265(2), 933-937.
6. Juarez-Mercado K E, Prieto-Martinez F D, Sanchez-Cruz N, et al. DNA Methyltransferase Inhibitors with Novel Chemical Scaffolds[J]. bioRxiv. 2020
7. Chen F, Xu Y, Wang J, et al. Relaxation Effect of Patchouli Alcohol in Rat Corpus Cavernous and Its Underlying Mechanisms[J]. Evidence-Based Complementary and Alternative Medicine. 2020, 2020.
8. Capoci I R G, Faria D R, Sakita K M, et al. Repurposing approach identifies new treatment options for invasive fungal disease[J]. Bioorganic chemistry. 2019 Mar;84:87-97.
9. Ju?rez-Mercado K E, Prieto-Mart?nez F D, S?nchez-Cruz N, et al. Expanding the Structural Diversity of DNA Methyltransferase Inhibitors[J]. Pharmaceuticals. 2021, 14(1): 17.