Pregnenolone monosulfate sodium salt
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Pregnenolone monosulfate sodium salt is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium salt can protect the brain from cannabis intoxication. Pregnenolone monosulfate sodium salt acts as a signaling-specific inhibitor of the cannabinoid CB1 receptor. Pregnenolone monosulfate sodium salt also inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors.
CAS:
1852-38-6
Formula:
C21H31NaO5S
Molecular Weight:
418.52
Purity:
0.98
SMILES:
[H][C@@]12CC[C@H](C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@H](CC[C@]12C)OS(=O)(=O)O[Na]
References
1. Vall?e M, et al. Pregnenolone can protect the brain from cannabis intoxication. Science. 2014 Jan 3;343(6166):94-8.
2. Ducharme N, et al. Brain distribution and behavioral effects of progesterone and pregnenolone after intranasal or intravenous administration. Eur J Pharmacol. 2010 Sep 1;641(2-3):128-34.