Parecoxib sodium
| Code | Size | Price |
|---|
| TAR-T1780L-50mg | 50mg | £166.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T1780L-100mg | 100mg | £229.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Parecoxib is a cyclooxygenase-2 inhibitor used for the short-term treatment of postoperative pain in adults. Parecoxib is a water-soluble and injectable prodrug of valdecoxib. Parecoxib is a COX2 selective inhibitor in the same category as celecoxib and rofecoxib. ketorolac has a much higher gastrointestinal toxicity profile compared to most other nonsteroidal anti-inflammatory drugs including ibuprofen and Naprosyn.
CAS:
198470-85-8
Formula:
C19H17N2NaO4S
Molecular Weight:
392.4
Purity:
0.98
SMILES:
[Na+].CCC(=O)[N-]S(=O)(=O)c1ccc(cc1)-c1c(C)onc1-c1ccccc1
References
1. Lv N, Kong Y, Mu L, Pan T, Xie Q, Zhao M. Effect of perioperative parecoxib sodium on postoperative pain control for transcatheter arterial chemoembolization for inoperable hepatocellular carcinoma: a prospective randomized trial. Eur Radiol. 2016 Oct;26(10):3492-9. doi: 10.1007/s00330-016-4207-8. Epub 2016 Jan 22. PubMed PMID: 26801163.
2. Cui W, Yu X, Zhang H. The Study of Different Approaches of Parecoxib Sodium Pretreatment on the Behavior of Rats with Neuropathic Pain. Cell Biochem Biophys. 2015 May;72(1):137-40. doi: 10.1007/s12013-014-0424-4. PubMed PMID: 25572054.
3. Chen H, Luo A. Safety and Efficacy Study of the Cyclooxygenase-2 Inhibitor Parecoxib Sodium Applied for Postoperative Analgesia After Endo-Nasal Operation. Pain Pract. 2016 Apr;16(4):467-72. doi: 10.1111/papr.12294. Epub 2015 Apr 10. PubMed PMID: 25857847.
4. Liu WJ, Zhong ZJ, Cao LH, Li HT, Zhang TH, Lin WQ. Paclitaxel-induced lung injury and its amelioration by parecoxib sodium. Sci Rep. 2015 Aug 10;5:12977. doi: 10.1038/srep12977. PubMed PMID: 26256764; PubMed Central PMCID: PMC4530342.