L-Leucine-p-nitroanilide

TargetMol
Product Code: TAR-T20445
Supplier: TargetMol
CodeSizePrice
TAR-T20445-500mg500mg£270.00
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Quantity:
TAR-T20445-1g1g£389.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
L-Leucine-p-nitroanilide is a substrate. It is used for the colorimetric determination of leucine aminopeptidase.
CAS:
4178-93-2
Formula:
C12H17N3O3
Molecular Weight:
251.286
Purity:
0.98
SMILES:
CC(C)C[C@H](N)C(=O)Nc1ccc(cc1)[N+]([O-])=O

References

1. Lin SH, Van Wart HE. Effect of cryosolvents and subzero temperatures on the hydrolysis of L-leucine-p-nitroanilide by porcine kidney leucine aminopeptidase. Biochemistry. 1982 Oct 26;21(22):5528-33. PubMed PMID: 7171573. 2. Shimasue A, Sugimoto Y, Tsubokura T. [No blank method using L-leucine-p-nitroanilide as substrate for the assay of serum leucine aminopeptidase (author's transl)]. Rinsho Byori. 1977 Feb;25(2):157-60. Japanese. PubMed PMID: 558393. 3. Zhu X, Barman A, Ozbil M, Zhang T, Li S, Prabhakar R. Mechanism of peptide hydrolysis by co-catalytic metal centers containing leucine aminopeptidase enzyme: a DFT approach. J Biol Inorg Chem. 2012 Feb;17(2):209-22. doi: 10.1007/s00775-011-0843-2. Epub 2011 Sep 15. PubMed PMID: 21918843. 4. Hern?ndez-Moreno AV, Villase?or F, Medina-Rivero E, P?rez NO, Flores-Ortiz LF, Saab-Rinc?n G, Luna-B?rcenas G. Kinetics and conformational stability studies of recombinant leucine aminopeptidase. Int J Biol Macromol. 2014 Mar;64:306-12. doi: 10.1016/j.ijbiomac.2013.12.023. Epub 2013 Dec 22. PubMed PMID: 24368112.