TargetMol

Lithocholic acid

Product Code:
 
TAR-T2202
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2202-500mg500mg£107.00
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Quantity:
TAR-T2202-1mL1 mL * 10 mM (in DMSO)£111.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2202-1g1g£115.00
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This product comes from: United States.
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Further Information

Bioactivity:
Lithocholic acid is a bile acid formed from chenodeoxycholate by bacterial action, usually conjugated with glycine or taurine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as cholagogue and choleretic.
CAS:
434-13-9
Formula:
C24H40O3
Molecular Weight:
376.58
Pathway:
Metabolism; Autophagy; ; Apoptosis
Purity:
0.9998
SMILES:
C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]1[C@H]2CC[C@H]2[C@@]1(CC[C@H](C2)O)C)C
Target:
Apoptosis; FXR; Endogenous Metabolite; Autophagy

References

1. Staudinger JL, et al. PNAS, 2001, 98(6), 3369-3374. 2. Parks DJ, et al. Science, 1999, 284(5418), 1365-1368. 3. Makishima M, et al. Science, 2002, 296(5571), 1313-1316. 4. Ogawa A, et al. Jpn J Cancer Res, 1998, 89(11), 1154-1159. 5. Kozoni V, et al. Carcinogenesis, 2000, 21(5), 999-1005. 6. Yang R, et al. Metabolomic analysis of cholestatic liver damage in mice. Food Chem Toxicol. 2018 Jul 14;120:253-260.