Phenidone

TargetMol
Product Code: TAR-T22398
Supplier: TargetMol
CodeSizePrice
TAR-T22398-500mg500mg£103.00
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Quantity:
TAR-T22398-1mL1 mL * 10 mM (in DMSO)£107.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Phenidone is a dual inhibitor of cyclooxygenases and lipoxygenases that ameliorates rat paralysis in experimental autoimmune encephalomyelitis by suppressing its target enzymes[1]. The lipoxygenase inhibitor phenidone is a potent hypotensive agent in the spontaneously hypertensive rat[2].
CAS:
92-43-3
Formula:
C9H10N2O
Molecular Weight:
162.192
Pathway:
Neuroscience; Metabolism; Immunology/Inflammation
Purity:
0.9934
SMILES:
OC1=NN(CC1)c1ccccc1
Target:
Lipoxygenase; COX

References

1. Moon C, et al. Phenidone, a dual inhibitor of cyclooxygenases and lipoxygenases, ameliorates rat paralysis in experimental autoimmune encephalomyelitis by suppressing its target enzymes. Brain Res. 2005;1035(2):206-210. 2. Stern N, et al. The lipoxygenase inhibitor phenidone is a potent hypotensive agent in the spontaneously hypertensive rat. Am J Hypertens. 1993;6(1):52-58. 3. Petrakiev A, et al. Emission spectral analysis using photographic plates treated with a phenidone developer. Talanta. 1969;16(12):1583-1587.