L-Pyrohomoglutamic Acid

TargetMol
Product Code: TAR-T36110
Supplier: TargetMol
CodeSizePrice
TAR-T36110-500mg500mg£136.00
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Quantity:
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
L-Pyrohomoglutamic acid is an amino acid building block.1,2It has been used in the synthesis of ligands for FK506-binding proteins (FKBPs) and histone deacetylase (HDAC) inhibitors.
CAS:
34622-39-4
Formula:
C6H9NO3
Molecular Weight:
143.142
Purity:
0.98
SMILES:
OC(=O)[C@@H]1CCCC(=O)N1

References

Pomplun, S., Wang, Y., Kirschner, A., et al.Rational design and asymmetric synthesis of potent and neurotrophic ligands for FK506-binding proteins (FKBPs)Angew. Chem. Int. Ed.54(1)345-348(2015) Taddei, M., Cini, E., Giannotti, L., et al.Lactam based 7-amino suberoylamide hydroxamic acids as potent HDAC inhibitorsBioorg. Med. Chem. Lett.24(1)61-64(2014)