Thalidomide-5,6-F

TargetMol
Product Code: TAR-T38985
Supplier: TargetMol
CodeSizePrice
TAR-T38985-500mg500mg£191.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Thalidomide-5,6-F is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5,6-F can be connected to the ligand for protein by a linker to form PROTACs.
CAS:
1496997-41-1
Formula:
C13H8F2N2O4
Molecular Weight:
294.214
Purity:
0.98
SMILES:
Fc1cc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2cc1F

References

Liu K, et al. Design and biological characterization of hybrid compounds of curcumin and thalidomide for multiple myeloma. Org Biomol Chem. 2013;11(29):4757-4763.