Hemin
| Code | Size | Price |
|---|
| TAR-T5515-1g | 1g | £104.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T5515-1mL | 1 mL * 10 mM (in DMSO) | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Hemin is an iron-containing porphyrin and Heme oxygenase (HO)-1 inducer.
CAS:
16009-13-5
Formula:
C34H32ClFeN4O4
Molecular Weight:
651.95
Pathway:
Apoptosis; Cell Cycle/Checkpoint; Autophagy
Purity:
0.9959
SMILES:
CC1=C(CCC(O)=O)C2=[N+]3C1=Cc1c(C)c(C=C)c4C=C5C(C)=C(C=C)C6=[N+]5[Fe--]3(Cl)(n14)n1c(=C6)c(C)c(CCC(O)=O)c1=C2
Target:
Mitophagy; Ferroptosis; Autophagy
References
Vanova K , Boukalova S , Gbelcova H , et al. Heme oxygenase is not involved in the anti-proliferative effects of statins on pancreatic cancer cells[J]. BMC Cancer, 2016, 16(1):309.
Chen HH, et al. Heme oxygenase-1 ameliorates kidney ischemia-reperfusion injury in mice through extracellular signal-regulated kinase 1/2-enhanced tubular epithelium proliferation. Biochim Biophys Acta. 2015 Oct;1852(10 Pt A):2195-201.
Owen J E , Bishop G M , Robinson S R . Uptake and Toxicity of Hemin and Iron in Cultured Mouse Astrocytes[J]. Neurochemical Research, 2016.