3-Bromopyruvic acid

TargetMol
Product Code: TAR-T5882
Supplier: TargetMol
CodeSizePrice
TAR-T5882-500mg500mg£103.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T5882-1g1g£109.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

1 / 1

Further Information

Bioactivity:
3-Bromopyruvic acid is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition. It is inhibitor of tumour cell energy metabolism and chemopotentiator of platinum drugs.
CAS:
1113-59-3
Formula:
C3H3BrO3
Molecular Weight:
166.958
Pathway:
Apoptosis; Metabolism; Autophagy
Purity:
0.9896
SMILES:
OC(=O)C(=O)CBr
Target:
Apoptosis; Hexokinase; Autophagy

References

Leng X , Peng J , Yu X , et al. 3-Bromopyruvic Acid, A Hexokinase II Inhibitor, is an Effective Antitumor Agent on the Hepatoma Cells : in vitro and in vivo Findings[J]. Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry - Anti-Cancer Agents), 2014, 14(5):-.