TargetMol

1,4-D-Gulonolactone

Product Code:
 
TAR-T4719
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4719-1g1g£103.00
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Quantity:
TAR-T4719-1mL1 mL * 10 mM (in DMSO)£107.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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Further Information

Bioactivity:
L-Gulonolactone (also known as reduced ascorbic acid, RAA) is the substrate of the enzyme L-gulono-1,4-lactone oxidoreductase (EC 1.1.3.8), which catalyzes the last step of the biosynthesis of L-ascorbic acid (vitamin C) in plants and animals. The enzyme L-Gulono-1,4-lactone oxidase is missing in scurvy-prone, vitamin C-deficient animals, such as humans. L-Gulonolactone is present in human blood and has been used as one of the markers to compare changes in exercise-induced oxidative stress. (PMID: 16956367 , 16494601 ).
CAS:
6322-07-2
Formula:
C6H10O6
Molecular Weight:
178.14
Pathway:
Metabolism;
Purity:
0.9974
SMILES:
OC[C@@H](O)[C@@H]1OC(=O)[C@H](O)[C@@H]1O
Target:
Endogenous Metabolite

References

Wolucka B A , Communi D . Mycobacterium tuberculosis possesses a functional enzyme for the synthesis of vitamin C, L-gulono-1,4-lactone dehydrogenase[J]. Febs Journal, 2006, 273(19):4435-4445. Steinberg J G , Delliaux, St?phane, Jammes Y . Reliability of different blood indices to explore the oxidative stress in response to maximal cycling and static exercises.[J]. Clinical Physiology & Functional Imaging, 2010, 26(2):106-112.