Pamoic acid
| Code | Size | Price |
|---|
| TAR-T8353-1g | 1g | £103.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T8353-1mL | 1 mL * 10 mM (in DMSO) | £107.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.
CAS:
130-85-8
Formula:
C23H16O6
Molecular Weight:
388.375
Pathway:
Endocrinology/Hormones; GPCR/G Protein
Purity:
0.9999
SMILES:
OC(=O)c1cc2ccccc2c(Cc2c(O)c(cc3ccccc23)C(O)=O)c1O
Target:
GPR
References
Naresh Mittapelly , Ramakrishna Rachumallu , Gitu Pandey,et al.Investigation of Salt Formation Between Memantine and Pamoic Acid: Its Exploitation in Nanocrystalline Form as Long Acting Injection.Eur J Pharm Biopharm. 2016 Apr;101:62-71.
Zhao P , Sharir H , Kapur A , et al. Targeting of the Orphan Receptor GPR35 by Pamoic Acid: A Potent Activator of Extracellular Signal-Regulated Kinase and ?-Arrestin2 with Antinociceptive Activity[J]. Molecular Pharmacology, 2010, 78(4):560-568.