TargetMol

Pamoic acid

Product Code:
 
TAR-T8353
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8353-1g1g£103.00
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Quantity:
TAR-T8353-1mL1 mL * 10 mM (in DMSO)£107.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.
CAS:
130-85-8
Formula:
C23H16O6
Molecular Weight:
388.375
Pathway:
Endocrinology/Hormones; GPCR/G Protein
Purity:
0.9999
SMILES:
OC(=O)c1cc2ccccc2c(Cc2c(O)c(cc3ccccc23)C(O)=O)c1O
Target:
GPR

References

Naresh Mittapelly , Ramakrishna Rachumallu , Gitu Pandey,et al.Investigation of Salt Formation Between Memantine and Pamoic Acid: Its Exploitation in Nanocrystalline Form as Long Acting Injection.Eur J Pharm Biopharm. 2016 Apr;101:62-71. Zhao P , Sharir H , Kapur A , et al. Targeting of the Orphan Receptor GPR35 by Pamoic Acid: A Potent Activator of Extracellular Signal-Regulated Kinase and ?-Arrestin2 with Antinociceptive Activity[J]. Molecular Pharmacology, 2010, 78(4):560-568.